Searchable abstracts of presentations at key conferences in endocrinology

ea0077oc3.2 | Metabolism, Obesity and Diabetes | SFEBES2021

Comparing the transcriptional landscape between lean and obese mice within the small intestinal segments

Jacobs Margot , West Jason , Rajagopalan Harith , Bewick Gavin

Background: Obesity is a complex metabolic disease characterised by excess adipose tissue, that increases the risk of comorbidities such as type II diabetes. Interventions that rearrange the gut architecture or exclude nutrients from the duodenum promote immediate and long-term anti-diabetic effects, placing the gut front and centre in obesity and diabetes pathology and treatment. Currently, little is known about the pathological changes which occur in the small intestine (SI)...